Table 1.

Serum BUN and creatinine in experimental animals

Genotype	Serum BUN (mg/dl)		Serum Creatinine (mg/dl)
	Sham	CKD	Sham	CKD
RCOK1+/+	30.5±1.7	85.4±7.6a	0.39±0.05	1.39±0.12a
ROCK1−/−	32.6±2.7	87.9±5.7a	0.35±0.04	1.47±0.16a
lox/lox	27.5±3.1	94.8+8.2a	0.42+0.03	1.58+0.21a
MPKO	28.4±3.7	89.4+5.5a	0.37+0.04	1.51+0.11a

Serum BUN and creatinine are shown for the experimental mice; at least 7 animals were examined in each group (n=7–12). Values are presented as mean±SEM.

^aP<0.01 versus sham.