Table 5. BSH effect on markers of systemic NK cells.
Marker | Difference day2 minus day-1 | Difference day21 minus day-1 | ||||
---|---|---|---|---|---|---|
ASH | BSH | p value | ASH | BSH | p value | |
CD56 | -447±540 | -187±564 | 0.28 | -433±957 | -42.9±929 | 0.30 |
CD16 | 3792±5519 | 2083±4728 | 0.43 | -1401±7858 | -353.3±6378 | 0.71 |
CD314 (NKG2D) | -90.6±135 | -26.8±163 | 0.33 | -53.6±111 | 44.5±107 | 0.038* |
CD158b | -316±365 | -185±236 | 0.31 | -50.2±771 | -203±375 | 0.52 |
CD183 (CXCR3) | -2379±6931 | -3497±9024 | 0.76 | -2041±6191 | -2854±8176 | 0.81 |
Following NK cell enrichment, NK cells were stimulated with PMA/Ionomycin and blocked with Brefeldin A (only intracellular markers) for 4hrs. The differences of day2 or day21 and day-1 are shown. Data are presented as mean±std.dev. N = 9–14.
* significantly different (p<0.05), tested with two sample t test.