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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Neuropharmacology. 2014 Nov 1;90:33–41. doi: 10.1016/j.neuropharm.2014.10.017

Table 1.

Kynurenine levels (μM) in plasma of dams and their fetuses/pups

Daily exposure to kynurenine from ED15 (100 mg/day; EKYN) raised kynurenine levels in the plasma of dams and fetuses on ED21. Data are the mean ± SEM (ECON: n = 4 litters; EKYN: n = 3 litters). By PD2, kynurenine levels were similar in dams (ECON: n = 4; and EKYN: n = 4) and pups (ECON: n = 4 litters; EKYN: n = 4 litters).

Condition ED21 PD2
FETUS DAM PUP DAM
ECON 4.68 ± 1.9 1.3 ± 0.1 0.71 ± 0.17 1.54 ± 0.03
EKYN 37.1 ± 9.8 30.2 ± 11.3 0.99 ± 0.34 1.81 ± 0.31
t-test t5= −3.820; P=0.012 t5=−3.051; P=0.028 t6=−0.729; P=0.493 t6 = −0.838; P=0.4383