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Structure of Lp(a)
| Discovered by Berg in 1963 |
| Consists of cholesterol rich LDL with one molecule of apoB 100 & apo(a) attached via disulfide bonds |
| Apo(a) glycoprotein confers its characteristic properties on Lp(a) |
| Has 10 types of kringle 4 which is the basis of the different isoform size variablity |
| Smaller the size of apo(a) isoform, higher the plasma concentration of Lp(a) |
