Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Athero-thrombogenic mechanisms of Lp(a)
| Binds to the surface of fibrin & cell membranes, thus competing with plasminogen & inhibiting its activation |
| Cholesterol deposition in the arterial wall |
| Enhances foam cell formation |
| Promotes O2-free radicals in monocytes |
| Promotes smooth muscle cell proliferation |
| Induces monocyte-chemotactic activity in subendothelial space |
