Table 1.
Metal content in different brain regions of rats exposed to chronic Cu toxicity (90 days)
| Brain region | Copper content (μg Cu/g of wet tissue weight) | Zinc content (μg Zn/g of wet tissue weight) | Iron content (μg Fe/g of wet tissue weight) | |||
|---|---|---|---|---|---|---|
| Control | Cu-intoxicated | Control | Cu-intoxicated | Control | Cu-intoxicated | |
| Cortex | 2.2 ± 0.06 | 9.19 ± 0.54** | 23.3 ± 0.91 | 21.97 ± 1.58# | 24.87 ± 0.11 | 24.23 ± 0.12# |
| Striatum | 2.18 ± 0.07 | 11.31 ± 0.67** | 25.34 ± 0.67 | 25.11 ± 1.3# | 25.14 ± 0.07 | 25.31 ± 0.12# |
| Cerebellum | 2.69 ± 0.08 | 5.07 ± 0.11** | 32.93 ± 0.12 | 34.17 ± 2.6# | 30.13 ± 0.16 | 30.58 ± 0.19# |
Values are expressed as mean ± SEM (n = 8/group)
** p < 0.01; statistical significance with respect to controls
#Not significant