TABLE 2.

Plasma ET-1, serotonin and nitrite in male and female rats treated once a week for 12 weeks with DAPM (25 mg/kg) or ethanol vehicle

	ET-1 (pg/ml)		Serotonin (ng/ml)		Nitrite (nM)
	Male	Female	Male	Female	Male	Female
Vehicle	6.53 ± 0.57	9.16 ± 1.27	43.1 ± 6.33	54.2 ± 3.71	117 ± 7.64	283 ± 58.7**
DAPM	7.85 ± 1.37	14.5 ± 0.39*	60 ± 7.87	99.8 ± 19.8*	157 ± 30.5	140 ± 14.8*

Data expressed as means ± SEM, n = 4–6 animals per group.

*Indicates significant difference from vehicle-treated animals of the same sex, p < .05. **Indicates significant difference from males of same treatment group, p < .05.