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. 2015 Jun 26;147(1):235–245. doi: 10.1093/toxsci/kfv126

TABLE 2.

Plasma ET-1, serotonin and nitrite in male and female rats treated once a week for 12 weeks with DAPM (25 mg/kg) or ethanol vehicle

ET-1 (pg/ml)
Serotonin (ng/ml)
Nitrite (nM)
Male Female Male Female Male Female
Vehicle 6.53 ± 0.57 9.16 ± 1.27 43.1 ± 6.33 54.2 ± 3.71 117 ± 7.64 283 ± 58.7**
DAPM 7.85 ± 1.37 14.5 ± 0.39* 60 ± 7.87 99.8 ± 19.8* 157 ± 30.5 140 ± 14.8*

Data expressed as means ± SEM, n = 4–6 animals per group.

*Indicates significant difference from vehicle-treated animals of the same sex, p < .05. **Indicates significant difference from males of same treatment group, p < .05.