Subject area	Biology, Epigenetic
More specific subject area	Hematopoiesis, DNA damage, deubiquitinating enzymes (DUBs)
Type of data	Text file, graph, figure, table
How data was acquired	High-throughput RNA sequencing using the Illumina HiSeq 2000 (Mus musculus). qRT-PCR by SYBR Green assays.
Data format	Raw, processed and analyzed
Experimental factors	Cell isolation by FACS sorting, cell culture of LPS-stimulated B cells, preparation of RNA libraries by standard Illumina TruSeq RNA Sample Prep protocols.
Experimental features	Genome-wide expression profiling of mouse hematopoietic stem and progenitor cells (LSK cells), naïve splenic B cells and in vitro lipopolysaccharide (LPS)- stimulated B cells (activated B cell). qRT–PCR on LSK cells by SYBR Green assays.
Data source location	Amsterdam, The Netherlands
Data accessibility	The raw data discussed in this publication have been deposited in NCBI’s Gene Expression Omnibus[5]and are accessible through GEO Series accession no. GSE58 495. Validation of the RNA-seq data sets is available with this article.