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. 2016 Jan 28;12(1):e1004658. doi: 10.1371/journal.pcbi.1004658

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© 2016 Al-Ghalith et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 5 — Example of the Burrows-Wheeler transform on both small sequences (top) and a concatenated longer sequence (bottom). The concatenated sequence is more easily searchable using the LF walk. NINJA forms a BWT-compatible concatesome that can be used interchangeably among various BWT-based aligners as an artificial reference chromosome. This concatenated sequence serves as a reference against which environmentally-obtained marker sequences are aligned.