Table 1.

Characteristics of the patient population.

Group	n	Female (%)	Age	T1D duration
A. Discovery dataset
Controls	665	53.2	22.8 ± 18.1	NA
T1D (all)	584	53.9	29.3 ± 18.5	13.2 ± 12.2
T1D no complications	453	53.4	23.2 ± 15.2	9.5 ± 8.8
T1D any complication	131	55.7	50.3 ± 12.4	26.2 ± 13.3
T1D with 1 complication	78	55.1	49.0 ± 13.6	22.1 ± 13.7
T1D with 2 complications	28	53.6	50.2 ± 9.3	31.5 ± 8.9
T1D with ≥3 complications	25	60.0	54.6 ± 10.4	32.8 ± 11.6
B. Confirmation dataset
Controls	1328	55.6	22.2 ± 18.0	NA
T1D (all)	1085	51.9	30.6 ± 18.2	15.2 ± 13.2
T1D no complications	830	49.5	24.9 ± 15.8	10.8 ± 10.5
T1D any complication	255	59.6	49.0 ± 12.6	29.2 ± 11.2
T1D with 1 complication	142	59.9	45.7 ± 13.5	26.4 ± 10.8
T1D with 2 complications	62	66.1	51.6 ± 9.1	31.9 ± 11.5
T1D with ≥3 complications	51	51.0	54.8 ± 10.6	33.8 ± 9.7