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. 2016 Jan 29;10:1. doi: 10.3389/fnins.2016.00001

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Copyright © 2016 Nair, Sasidharan, John, Mehrotra and Kutty.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Structure of an ANGEL trial. The visual stimulus (Stim) has a pre-stimulus mask (where paired tone stimuli may begin) and a post stimulus mask during which the subject may respond. The tone for Corollary Discharge (CD) may be presented (C) as soon as the subject responds or after a random interval (R) at the end of the response window timeout. Only one of the three paired tone sets are presented in a trial. Every paired-tone trial is followed by three trials with just a blank sound clip. There is a fixed minimum baseline (with mask) of 200 ms at the end of each trial which may be randomly extended by up to an additional 700 ms. Average trial length is 1550 ms (ranging from 1200 to 1900 ms).