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. 2015 Nov 15;5(12):3612–3623.

Figure 2.

Figure 2

NDV/FMW exhibits oncolytic activity in lung cancer spheroid cultures. 3D cultures of H460 and MOR cells were mock-infected or infected with NDV/FMW (MOI = 1; 48 h) and examined for spheroid (A) and colony formation (B). Results are expressed as number of spheroids/1000 cells and colonies ± SD from three independent experiments (scale bar = 100 μm). H460 and MOR spheroids were mock-infected or infected with NDV/FMW (MOI = 10, 1, or 0.1) and stained with PI (C). Spheroids mock-infected or infected with NDV/FMW at MOIs (0.1, 1 and 10) were stained with PI at 48 h and imaged under phase contrast and red fluorescence microscopy (scale bar = 50 μm).