Table 1.
Effect of different drug treatments on In vivo tumor growth.
| S.no | Treatment | Viable tumor cells count (105 Cells/ml) | Weight change (gm) | MST | % ILS |
|---|---|---|---|---|---|
| 1 | DLA | 558 ± 7.45 | 13.5 ± 0.96 | 12.2 ± 1.28 | - |
| 2 | DLA + CYLP (10 mg/kg) | 9.3 ± 1.22ˆ*** | 5.5 ± 0.02ˆ*** | 28.4 ± 2.12 | 132.7 |
| 3 | DLA + GF (100 mg/kg) | 62.9 ± 4.17ˆ*** | 8.2 ± 0.74ˆ*** | 16.8 ± 1.72 | 37.7 |
| 4 | DLA + GF (200 mg/kg) | 22 ± 2.72ˆ*** | 6.3 ± 0.57ˆ*** | 20.3 ± 1.61 | 66 |
| 5 | DLA + GB (200 mg/kg) | 105.6 ± 4.94ˆ*** | 7.3 ± 0.42ˆ*** | 14.5 ± 1.37 | 18.85 |
| 6 | DLA + GL (200 mg/kg) | 44.8 ± 3.47ˆ*** | 5.6 ± 0.16ˆ*** | 18.4 ± 1.98 | 50.8 |
All the results were expressed in mean ± SD (n = 10). ***P ≤ 0.001 in comparison of drug treated DLA mice with untreated DLA mice. DLA, Dalton’s lymphoma; CYLP, Cyclophosphamide; GF, G. morella fruit methanol extract; GB, G. morella bark methanol extract; GL, G. morella leaf methanol extract.