Table 3.
Effect of different drug treatments on serum biochemical parameters.
S.no | Treatment | AST | ALT | ALP |
---|---|---|---|---|
1 | Control | 41.14 ± 2.36 | 34.18 ± 1.79 | 128.52 ± 2.21 |
2 | DLA | 87.17 ± 3.11∗∗∗ | 57.19 ± 2.41∗∗∗ | 247.35 ± 3.62∗∗∗ |
3 | DLA + CYLP (10 mg/kg) | 49.47 ± 2.62$$$ | 42.33 ± 1.87$$$ | 147.89 ± 1.68$$$ |
4 | DLA + GF (100 mg/kg) | 67.47 ± 3.38$$$ | 49.51 ± 2.64$$$ | 202.91 ± 2.48$$$ |
5 | DLA + GF (200 mg/kg) | 56.92 ± 2.76$$$ | 44.58 ± 3.11$$$ | 177.77 ± 3.15$$$ |
6 | DLA + GB (200 mg/kg) | 73.92 ± 3.61$$ | 52.71 ± 2.86$$ | 231.09 ± 4.23$ |
7 | DLA + GL (200 mg/kg) | 61.46 ± 1.94$$$ | 47.96 ± 1.82$$$ | 188.24 ± 2.27$$$ |
All the results were expressed in mean ± SD (n = 10). ***P ≤ 0.001 comparison of DLA untreated mice with normal mice, $$$ P ≤ 0.00, $$ P ≤ 0.01 and $ P ≤ 0.05 comparison of drug treated DLA mice with DLA untreated mice. DLA, Dalton’s lymphoma; CYLP, Cyclophosphamide; GF, G. morella fruit methanol extract; GB, G. morella bark methanol extract; GL, G. morella leaf methanol extract.