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. 2015 Dec 1;192(11):1355–1365. doi: 10.1164/rccm.201412-2262OC

Figure 9.

Figure 9.

Plots showing expression of downstream transforming growth factor-β1 signaling in the lungs and livers of control and infected wild-type (WT) and Bmpr2+/− mice. (A) Lung plasminogen activation inhibitor 1 (PAI1) and (B) lung connective tissue growth factor (CTGF) (WT Cont n = 8, Bmpr2+/− Cont n = 8, WT infected n = 12, Bmpr2+/− infected n = 7), (C) liver PAI1 (WT Cont n = 5, Bmpr2+/− Cont n = 5, WT infected n = 5, Bmpr2+/− infected n = 7), and (D) liver CTGF (WT Cont n = 5, Bmpr2+/− Cont n = 5, WT infected n = 5, Bmpr2+/− infected n = 4). Data are presented as mean ± SEM. *P < 0.05 compared with WT control, **P < 0.01 compared with WT control, #P < 0.05 compared with Bmpr2+/− control, ##P < 0.01 compared with Bmpr2+/− control. Bmpr2 = bone morphogenetic protein type 2 receptor; Cont = control.