Table 3.

Association between Frail Phenotypes and Mean LT-VLA Disability

	SPPB (n = 253)	FFP (n = 254)
Model 1	0.27 (0.19–0.35)	0.28 (0.20–0.36)
Model 2	0.25 (0.17–0.34)	0.26 (0.19–0.34)
Model 3	0.12 (0.04–0.21)	0.18 (0.10–0.25)
Model 4	0.12 (0.04–0.21)	0.17 (0.09–0.25)

Definition of abbreviations: FFP = Fried Frailty Phenotype; LT-VLA = Lung Transplant Valued Life Activities; SPPB = Short Physical Performance Battery.

Effect estimates are increases in mean LT-VLA (95% confidence intervals) per 1 SD worsening in frailty score. Worsening is defined as a decrease in SPPB and an increase in FFP. Values greater than 0 indicate greater disability. An LT-VLA increase ≥0.3 is clinically meaningful.

Model 1: adjusted for center.

Model 2: model 1 + age, sex, diagnosis.

Model 3: model 2 + Lung Allocation Score.

Model 4: model 3 + FVC, body mass index.