Table 2.
Serum cytokine levels.
| HFD |
HFD + Exercise |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| WT |
AccDKI |
WT |
AccDKI |
|||||||||
| Average | ±SEM | N | Average | ±SEM | N | Average | ±SEM | N | Average | ±SEM | N | |
| Leptin (ρg/mL) | 10916.3 | 798.7 | 10 | 9783.7 | 776.9 | 7 | 6466.9∗∗∗ | 852.8 | 9 | 9570.4 | 920.7 | 10 |
| IL-6 (ρg/mL) | 9.9 | 0.6 | 10 | 7.9 | 1.0 | 6 | 8.0 | 0.5 | 10 | 10.9 | 1.1 | 10 |
| tPAI-1 (ρg/mL) | 2130.4 | 307.5 | 10 | 2624.3 | 855.2 | 7 | 2045.7 | 295.2 | 10 | 1950.1 | 263.5 | 10 |
| Resistin (ρg/mL) | 4156.0 | 300 | 10 | 4153.8 | 466.7 | 8 | 4080.1 | 450.6 | 9 | 4502.5 | 483.6 | 10 |
| TNF-α (ρg/mL) | Not detectable | 10 | Not detectable | 7 | Not detectable | 9 | Not detectable | 10 | ||||
| MCP-1 (ρg/mL) | Not detectable | 10 | Not detectable | 7 | Not detectable | 9 | Not detectable | 10 | ||||
Data are expressed as means ± SEM, ∗∗∗p < 0.001, for difference between WT sedentary vs WT exercise; §§p < 0.01, for difference from WT vs AccDKI, as determined by two-way ANOVA and Bonferonni post hoc test.