Figure 5. Correlation network within PPARγ-LBD depends on the oligomeric state.

(A) Intense correlations (GC_ij^intra > 0.6) displayed by PPARγ-LBD as a monomer (left) or as part of the full-length complex (right). (B) Correlation score per residue, computed for GC_ij^intra > 0.6. Residues written in red are known to be important for function. (C) Localization of some of the most intensely correlated residues on the LBD structure (marked in green in (B)).