Table 4. Associations of serum folate and vitamin B₁₂ levels with serum HCY levels stratified by serum hs-CRP levels.

	Coefficient estimates ± SE for HCY* (p-value)
	Unadjusted model	Multiple model
Folate
hs-CRP < 2 mg/L	-0.01 ± 0.002 (< 0.001)	-0.01 ± 0.002 (< 0.001)
hs-CRP ≥ 2 mg/L	-0.01 ± 0.004 (< 0.01)	-0.01 ± 0.004 (< 0.01)
Vitamin B12†
hs-CRP < 2 mg/L	-0.03 ± 0.004 (< 0.001)	-0.02 ± 0.004 (< 0.001)
hs-CRP ≥ 2 mg/L	0.004 ± 0.010 (0.69)	0.02 ± 0.009 (0.08)

In multiple models, serum levels of folate and vitamin B₁₂ were fitted as a continuous variable, and age, sex, body mass index, smoking status, alcohol consumption, physical activity, the presence of diabetes mellitus, hypertension, or dyslipidemia, and serum folate and vitamin B₁₂ levels were adjusted for.

HCY: homocysteine, hs-CRP: high-sensitive C-reactive protein, SE: standard error.

^*Log-transformed value; ^†The original value was divided by 100 because of small coefficient estimates.