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. 2016 Jan 29;15:51. doi: 10.1186/s12936-016-1097-9

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© Ponsuwanna et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Ratio of non-synonymous and synonymous mutation (N/S ratio) of HDP complex enzymes. Reported mutations from MalariaGen Database were used to calculate N/S ratio. For falcipain 2A and falcipain 2B, mutations found from manual sequencing of ANL1-ANL4 clones were included in the dataset. Ratio above 1 (marked by dashed line) might imply positive selection