Table 3.
Primary and secondary outcome measures during the TargET intervention period and in the preceding 6 year CAS(K) observational period
| CAS(K) (Observational period) | TargET (Intervention period) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Baseline | 18 mo | 36 mo | 54 mo | 72 mo | Baseline | 6 wk | 12 wk | ||
| Knee flexion ROM (degrees) | Mean (SD) | 28 | 123.7 (14.1) | - | 119.8(15.6) | - | 114.8(11.6) | 113.4(10.6) | 119.4(9.3) | 123.1(8.5) |
| Quadriceps isometric strength (KgF) | Mean (SD) | 13 | 16.3(9.5) | - | 15.4 (8.4) | - | 11.2(5.7) | 12.7(8.9) | 17.1(8.1) | 21.9(6.1) |
| Single-leg standing balance time (sec) | Median (IQR) | 41 | 6.0(9.0) | - | 3.5(8.0) | - | 2.0 (1.0) | 3.0(3.75) | 5.0(14.5) | 9.0(23.25) |
| WOMAC Pain (0–20) | Mean (SD) | 58 | 5.6(4.3) | 6.4 (4.2) | 7.5(3.9) | 7.5(4.2) | 7.7(3.8) | 7.5(3.7) | 5.7(3,7) | 5.3(3.4) |
| WOMAC Stiffness (0–8) | Mean (SD) | 58 | 2.7 (1.9) | 3.0(1.8) | 3.2(2.0) | 3.5(1.9) | 3.7(1.5) | 3.5(1.6) | 2.9(1.9) | 2.7(1.9) |
| WOMAC Physical Function (0–68) | Mean (SD) | 58 | 19.3(15.0) | 22.5(15.1) | 23.2(13.8) | 25.6(15.4) | 27.4(13.3) | 25.9(12.8) | 22.1(13.5) | 20.7(13.0) |