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. 2015 Dec 11;112(50):856–862. doi: 10.3238/arztebl.2015.0856

Table 1. Antiarrhythmic agents for pharmacological cardioversion*.

Agent Primary dose regimen Subsequent dose regimen Notes
Amiodarone 5 mg/kg BW IV over 1 h approx. 50 mg/h Potential acute adverse events: phlebitis. hypotension
Flecainide 2mg/kg BW IV over 10 min or 200–300 mg orally Not in patients with marked structural heart disease. risk of QRS interval widening. QT prolongation. and atrial flutter with fast conduction
Propafenone 2 mg/kg BW IV over 10 min or 450–600 mg orally Not in patients with marked structural heart disease. risk of QRS interval widening and atrial flutter with fast conduction
Vernakalant 3 mg/kg BW IV over 10 min Limited approval

*modified according to (4)