TABLE 2.

Sequences of oligonucleotides used for the real-time quantitative PCR

Gene	Sense	Anti-sense
Mouse bace1	5′-TTGTAGGGCTAGGGATGGTC-3′	5′-CCTAACCCTGCTGGATGAAT-3′
Mouse ps1	5′-CAATGGTGTGGTTGGTGAAT-3′	5′-GTTCCCAGAACCACTGTCCT-3′
Mouse nicastrin	5′-ACCAGGTGGAGGATCTTCTG-3′	5′-AGGACAACTTCAGGGACACC-3′
Mouse gapdh	5′-ACAACTTTGGCATTGTGGAA-3′	5′-GATGCAGGGATGATGTTCTG-3′
Human bace1	5′-TTGAAGCTGCAGTCAAATCC-3′	5′-CCAGAAACCATCAGGGAACT-3′
Human ps1	5′-CCGAAAGGTCCACTTCGTAT-3′	5′-CCACACCATTGTTGAGGAGT-3′
Human nicastrin	5′-GGGTTCCTGATTAAAGCCAA-3′	5′-CGTCACCCAAGTAGGACCTT-3′
Human gapdh	5′-GAAGGACTCATGACCACAGT-3′	5′-GTCATCATATTTGGCAGGTT-3′