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. 2015 Nov 23;291(5):2107–2118. doi: 10.1074/jbc.M115.693580

FIGURE 3.

FIGURE 3.

Elevations in O-GlcNAc increased Ins1 and Ins2 steady state mRNA levels in Min6 cells. A, extracted RNA from Min6 cells following 1 h treatment was used for mouse Ins1 mRNA quantification. Values are presented as -fold change to LG. B, RNA extraction was performed from Min6 cells as described above but used for mouse Ins2 mRNA quantification. Values are presented as -fold change to LG. C, extracted RNA from Min6 cells after 3 h of treatment was used for mouse Ins2 mRNA quantification. Values are presented as -fold change to LG (n ≥ 3). All data are shown as the mean ± S.E. Significance was determined using an ordinary one-way ANOVA. *, p < 0.05; **, p < 0.01; ***, p < 0.001 versus LG; #, p < 0.05 versus HG; ‖, p < 0.05 LG+GNS versus HG+GNS. NS, not significant.