TABLE 1.
Genotypes of offspring obtained from the cross of Prmt1flox/wt; Nes-Cre mice and Prmt1flox/flox mice
The numbers and percentages (in parentheses) of mice of various genotypes obtained by crosses of Prmt1flox/wt; Nes-Cre and Prmt1flox/flox at P0 are shown. The expected numbers and percentages of mice were calculated according to the total number of mice born and based on the expected Mendelian 1:1:1:1 ratio.
| Prmt1 | Cre | Expected no. (%) | Observed no. (%) |
|---|---|---|---|
| fl/w | − | 86 (25) | 71 (21) |
| fl/w | + | 86 (25) | 90 (26) |
| fl/fl | − | 86 (25) | 109 (32) |
| fl/fl | + | 86 (25) | 73 (21) |
| Total 343 (100) |