4. Accuracy of all parameters: data extracted at the lowest specificity.

Test (parameter)	Sensitivity1	Specificity1
GDx
Inferior sector	0.70 (0.65 to 0.74)	0.85 (0.21 to 0.87)
Nerve fibre indicator (NFI)	0.81 (0.77 to 0.85)	0.87 (0.84 to 0.90)
Superior sector	0.70 (0.65 to 0.73)	0.86 (0.83 to 0.88)
Temporal superior nasal inferior temporal (TSNIT) average	0.69 (0.64 to 0.74)	0.87 (0.84 to 0.90)
HRT
Cup Disk area ratio	0.65 (0.55 to 0.74)	0.91 (0.87 to 0.94)
Cup area	0.44 (0.31 to 0.58)	0.93 (0.89 to 0.95)
Cup shape measure	0.47 (0.37 to 0.57)	0.92 (0.88 to 0.95)
Cup volume	0.41 (0.29 to 0.54)	0.91 (0.87 to 0.94)
Frederick S. Mikelberg (FSM) discriminant function	0.60 (0.38 to 0.79)	0.92 (0.87 to 0.95)
Moorfields regression analysis (MRA)	0.68 (0.55 to 0.78)	0.88 (0.83 to 0.92)
Reinhard O.W. Burk (RB) discriminant function	0.56 (0.44 to 0.67)	0.93 (0.89 to 0.96)
Rim Volume	0.49 (0.38 to 0.60)	0.92 (0.89 to 0.95)
Rim area	0.54 (0.43 to 0.65)	0.91 (0.87 to 0.94)
Vertical cup disk ratio	0.71 (0.56 to 0.82)	0.92 (0.88 to 0.94)
OCT ONH
Cup disk area ratio	0.74 (0.64 to 0.81)	0.84 (0.81 to 0.87)
Cup disk horizontal ratio	0.67 (0.56 to 0.78)	0.81 (0.77 to 0.84)
Cup disk vertical ratio	0.80 (0.73 to 0.85)	0.86 (0.82 to 0.89)
Cup area	0.56 (0.32 to 0.77)	0.83 (0.79 to 0.87)
Cup volume	0.57 (0.38 to 0.73)	0.83 (0.80 to 0.86)
Disc area	0.32 (0.22 to 0.43)	0.83 (0.77 to 0.87)
Nerve head volume	0.66 (0.57 to 0.73)	0.81 (0.76 to 0.85)
Rim area	0.76 (0.67 to 0.82)	0.85 (0.81 to 0.88)
Rim volume	0.67 (0.59 to 0.74)	0.85 (0.79 to 0.90)
OCT RNFL
Average	0.78 (0.74 to 0.82)	0.89 (0.86 to 0.91)
Inferior sector	0.79 (0.75 to 0.82)	0.87 (0.84 to 0.89)
Nasal sector	0.43 (0.36 to 0.50)	0.86 (0.83 to 0.89)
Superior sector	0.71 (0.66 to 0.75)	0.87 (0.85 to 0.90)
Temporal sector	0.41 (0.33 to 0.50)	0.86 (0.83 to 0.89)

¹Summary sensitivity and specificity pairs of all parameters of each test. Parameters with the highest sensitivity are presented in bold character.
ONH: optic nerve head 
RNFL: retinal nerve fibre layer