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Causes of premature discontinuation (n=56).
| Cause | Eszopiclone n (%) n=25 | Zopiclone n (%) n=31 |
|---|---|---|
| Comorbidity | 1 (4.0) | - |
| Non-adherence to the protocol or treatment | 5 (20.0) | 4 (12.9) |
| Follow-up loss | 1 (4.0) | 2 (6.4) |
| Refusal to continue treatment | 3 (12.0) | 4 (12.9) |
| Withdrawal of consent | 2 (8.0) | 2 (6.4) |
| Intolerance to study medication | 9 (36.0) | 15 (48.4) |
| Other sleep-affecting drug use | 4 (16.0) | 4 (12.9) |
