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. 2015 Sep 7;46(1):1–42. doi: 10.3109/10408444.2015.1061477

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© 2015 The Author(s). Published by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/Licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Two-year (NTP 2000) vs 90-day (Dodd et al. 2012) metabolized dose–response in male and female rats following naphthalene exposure via inhalation (BMR of 10% extra risk for the 0.95 lower confidence limit on the BMD). Figures show the best-fit curve. See supplemental material for all modeling results. (A) Male rat respiratory epithelial hyperplasia dose–response from 2-year study (Logistic); (B) male rat respiratory epithelial hyperplasia dose–response from 90-day study (Weibull); (C) female rat olfactory epithelial hyperplasia dose–response from 2-year study (Log-Logistic with NO FIT); (D) female olfactory epithelial hyperplasia dose–response from 90-day study (Log-Logistic).