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. 2015 Dec 4;27(14):810–821. doi: 10.3109/08958378.2015.1115567

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© 2015 The Author(s). Published by Taylor & Francis.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.

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Figure 1. — Ratings of smell (A), irritation in the throat (B), and irritation in the eyes (C) by Visual Analogue Scale (VAS) in eight volunteers in the pilot study with stepwise increasing concentrations of acrolein (10 min per step). The curves represent the 25th, 50th (median), and 75th percentile. Logistic quantile regression analysis revealed significant increased throat irritation (p = 0.006) for the 50th percentile and a tendency of increased eye irritation (p = 0.066) for the highest percentile.