Figure 1.

Mean changes in concentrations (defined by average pixel value of each protein) of proteins derived from platelet lysate collected prior to (baseline, BL) and after 48 months of randomization to either Placebo, transdermal 17β-estradiol (E2) or oral conjugated equine estrogen (oCEE). Each bar represents the mean of pixel values per group (n = 10 in the placebo group, n = 11 in the tE2 group, and n = 9 in the oCEE group). The proteins are grouped according to proposed cell of origin. The list of abbreviations for the proteins is provided in the Supplementary Material.