Coronal and horizontal T1 weighted images (MEMRI), at 50 μm isotropic resolution, taken 24 h after iv infusion of 100 mM MnCl2 solution of 4 week old (a) control, (b) mutant and (c) mutant mouse after 1 week of doxycycline treatment mice and (d) the corresponding group intensity profile of 3 to 4 week old mice groups, and of 8 weeks old (e) control (f) mutant and (g) 7 week old mutant mouse after 3 weeks of doxycycline treatment and (h) the corresponding group intensity profile of 6 to 8 week old mice groups. The intensity profile was taken for each OB from lateral to medial side across the OB as shown by the arrows, and normalized to the minimum intensity for each OB. Group intensity profile is the average and sd, for both left and right OB of 3 to 4 week old control (n=4, total of 8 OBs), mutant (n=4, 8 OBs) and mutant mouse after 1 week of doxycycline treatment (n=4, 8 OBs) and 6 to 8 week old control (n=8, total of 16 OBs), mutant (n=4, 8 OBs), and mutant mouse after 3 weeks of doxycycline treatment (n=5, 10 OBs). ONL – olfactory nerve layer, GL – glomerular layer, Mi – mitral cell layer.