Table 2.
Control 3-4w | Mutant 3-4w | Mutant + Dox 1w | ||
---|---|---|---|---|
OB volume (mm3) | 19.8 ± 1.1 | 11.1 ± 0.9*** | 11.3 ± 0.5*** | |
Mi to Mi Distance (mm) | 0.42 ± 0.03 | 0.70 ± 0.06*** | 0.49 ± 0.04**### | |
Layer to minimum ratio | GL | 1.17 ± 0.05 | 1.03 ± 0.05*** | 1.07 ± 0.08*** |
Mi | 1.16 ± 0.06 | 1.10 ± 0.07* | 1.12 ± 0.09 |
Control 6-8w | Mutant 6-8w | Mutant + Dox 3w | ||
---|---|---|---|---|
OB volume (mm3) | 21.6 ± 1.5 | 9.1 ± 1.3*** | 14.1 ± 1.5***## | |
Mi to Mi Distance (mm) | 0.44 ± 0.06 | 0.65 ± 0.03*** | 0.45 ± 0.03### | |
layer to minimum ratio | GL | 1.13 ± 0.10 | 1.03 ± 0.07*** | 1.12 ± 0.08## |
Mi | 1.12 ± 0.10 | 1.10 ± 0.07 | 1.17 ± 0.08*## |
Mutant and mutant with Dox vs. control:
p < 0.05
p < 0.01
p < 0.001.
Mutant with Dox vs. mutant:
p < 0.05
p < 0.01
p < 0.001.
GL – glomerular layer, Mi – mitral cell layer.