Table 3.

OB volume, manganese enhancement of the different layers and the distance between the lateral and medial side of Mi of left and right OB in hAPP antibody treated mice groups.

		Control + antibody	Mutant + Vehicle	Mutant + antibody 1w	Mutant + antibody 3w
Left OB

OB volume (mm³)		10.3 ± 0.2	3.7 ± 0.5^***	4.0 ± 0.7^***	3.9 ± 0.4^***
Mi to Mi Distance (mm)		0.54 ± 0.05	0.67 ± 0.06^*	0.73 ± 0.07^**	0.69 ± 0.08^*
Layer to minimum ratio	GL	1.19 ± 0.05	1.06 ± 0.07^**	1.04 ± 0.06^***	1.01 ± 0.06^***
	Mi	1.16 ± 0.03	1.11 ± 0.10	1.11 ± 0.06	1.11 ± 0.07
Right OB

OB volume (mm³)		10.3 ± 0.3	3.8± 0.4^***	4.0 ± 0.6^***	3.9 ± 0.5^***
Mi to Mi Distance (mm)		0.51 ± 0.03	0.69 ± 0.07^***	0.71 ± 0.08^*	0.68 ± 0.05^**
Layer to minimum ratio	GL	1.15 ± 0.05	1.06 ± 0.05^**	1.03 ± 0.02^**	1.07 ± 0.06^*
	Mi	1.16 ± 0.05	1.12 ± 0.08	1.09 ± 0.07^*	1.12 ± 0.07

Mutant treated with vehicle or hAPP antibody vs. control for left and right OB:

p < 0.05

^**

p < 0.01

^***

p <0.001

GL – glomerular layer, Mi – mitral cell layer.