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. 2016 Jan 29;11(1):e0147706. doi: 10.1371/journal.pone.0147706

Fig 5. Survival of M. bovis BCG wild type, Δgdh mutant and Δgdh complemented strains in macrophages.

Fig 5

RAW 264.7 macrophages (A) or BMDM (B) were infected with M. bovis BCG wild type, Δgdh mutant and Δgdh complemented strains or (C) the ΔgltBD mutant and complemented strains and the survival of the bacteria was determined by measuring CFU obtained from macrophage lysates. Means and standard errors were calculated from three independent experiments. For the BMDM infections a different mouse was used in each experiment. Data was analysed by repeated measures two-way ANOVA with Bonferroni post-testing to compare mean CFU/ml of Δgdh mutant and wild type strains. * p < 0.05, ** p < 0.01, *** p < 0.001.