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. 2015 Dec 11;13(2):1111–1118. doi: 10.3892/mmr.2015.4675

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Sodium formate increased the basal levels of reactive oxygen species in 661W cells. The 661W cells treated with sodium formate (15 or 30 mM) were compared with the negative control by flow cytometric analysis using the fluorescent probe, DCF. (A) A shift to the right in the fluorescence intensity signal was observed for the 661W cells treated with formate. (B) The fluorescence intensity of DCF was measured in the 661W cells treated with (15 or 30 mM) or without sodium formate. (^*P<0.05; ^**P<0.01, sodium formate-treated cells, vs. the control). DCF, dichlorofluorescein.