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. 2015 Dec 4;13(2):1163–1171. doi: 10.3892/mmr.2015.4642

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Copyright: © Bo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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β-catenin mediates the effects of Wnt5a on pancreatic cancer cells. (A) Western blot analysis. Tumor cells were grown and transfected with β-catenin siRNA and then treated with recombinant Wnt5a protein prior to western blot analysis. (B) Flow cytometric assay of apoptosis. The cells were subjected to flow cytometric analysis to determine the percentage of apoptotic cells. The bar graph shows the results of densitometric analysis of the apoptotic assays. siRNA, small interfering RNA. The values are presented as the mean ± standard deviation. ^*P<0.05 of recombinant Wnt5a, vs. the control. ^**P<0.05 of β-catenin siRNA, vs. the control.