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. 2015 Dec 18;13(2):1501–1508. doi: 10.3892/mmr.2015.4696

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Copyright: © Ze et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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TSA increases the proliferation of WB-F344 oval cells. The WB-F344 oval cells were treated with 0 (control), 10, 20 and 40 µg/ml TSA and analyzed following (A) 24, (B) 48, (C) 72 and (D) 96 h. The cell proliferation index was assessed using a carboxyfluorescein succinimidyl ester assay coupled with flow cytometry. Representative histograms of cell proliferation were generated for WB-F344 hepatic oval cells treated with various concentrations of TSA (indicated in the panels). The proliferate index, relative to the control group, is indicated in each panel. TSA, tanshinone IIA; pro. ind, proliferative index.