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. 2015 Dec 14;13(2):1156–1162. doi: 10.3892/mmr.2015.4686

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Losartan alleviated 2,4,6-trinitrobenzenesulphonic acid (TNBS)-induced colitis. (A) Body weight change (percentage of original body weight) over time following various treatment methods (n=5/group). ^*P<0.05, ^**P<0.01 and ^***P<0.001 vs. the TNBS + Water group. (B) Representative colon morphology on day 4 after TNBS or ethanol (EtOH) injection. (C) Macroscopic score according to colonic morphology. (D) Representative hematoxylin & eosin staining. Original magnification, ×100. (E) Microscopic scoring of each colon (n=5/group). ^#P>0.05, ^**P<0.01 and ^***P<0.001.