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. 2015 Dec 14;13(2):1186–1194. doi: 10.3892/mmr.2015.4685

Figure 2.

Figure 2

VDR KO mice exhibit greater pulmonary edema than VDR WT mice. WT and KO mice were treated with PBS or LPS intratracheally. Lung samples were harvested and analyzed 12 h later. (A) Wet-dry ratio of lung weight, (B) BALF protein concentration, (C) BALF to serum FD4 ratio and (D) MPO activity of lung lysates of different mice. Data are presented as mean ± standard deviation. #P>0.05, *P<0.05, ***P<0.001. (n=5–6 per group). WT, wild-type; PBS, phosphate-buffered saline; KO, knockout; LPS, lipopolysaccharides; FD4, fluorescein isothiocyanate-conjugated 4 kDa dextran; MPO, myeloperoxidase.