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VD attenuates LPS-induced acute lung injury (ALI). (A) Representative hematoxylin and eosin staining of lung sections (magnification, x200). (B) ALI score and (C) MPO activity in wild-type and knockout mice treated with VD or VE. Data are represented as mean ± standard deviation. #P>0.05, *P<0.05, ***P<0.001 (n=5–6 per group). PBS, phosphate-buffered saline; LPS, lipopolysaccharides; VE, vehicle; VD, vitamin D (paricalcitol); MPO, myeloperoxidase; OD, optical density.
