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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Dec 3;36(2):398–403. doi: 10.1161/ATVBAHA.115.305970

Table 3.

Hazard ratios for incident cardiovascular disease and mortality according to APOL1 genotype.

AA 2 Risk
Alleles		 AA 0-1 Risk
Alleles		 White
(N=4964)		 P-value
(0-1 vs. 2 Risk
Alleles)
Individuals / Person-Years 91 / 882 707 / 7831 4964 / 60526
Cardiovascular Disease
Myocardial Infarction, N 19 84 779
    Adjusted Hazard Ratio (CI) 1.8 (1.1-3.0) Referent 1.1 (0.9-1.4) 0.02
Stroke, N 12 114 846
    Adjusted Hazard Ratio (CI) 0.9 (0.5-1.7) Referent 0.9 (0.7-1.1) 0.80
Congestive Heart Failure, N 23 182 1407
    Adjusted Hazard Ratio (CI) 1.0 (0.6-1.5) Referent 0.9 (0.7-1.0) 0.98
Mortality
Total Mortality, N 61 401 3366
    Adjusted Hazard Ratio (CI) 1.3 (1.0-1.7) Referent 1.0 (0.9-1.1) 0.05
Cardiovascular Mortality, N 23 159 1334
    Adjusted Hazard Ratio (CI) 1.3 (0.8-2.0) Referent 1.0 (0.8-1.1) 0.31
Non-Cardiovascular Mortality, N 38 240 2026
    Adjusted Hazard Ratio (CI) 1.4 (1.0-1.9) Referent 1.0 (0.8-1.1) 0.05