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. Author manuscript; available in PMC: 2016 Jan 29.
Published in final edited form as: J Med Chem. 2016 Jan 13;59(2):592–608. doi: 10.1021/acs.jmedchem.5b01369

Scheme 3. Preparation of N-acyl substituted diamidine analogs.

Scheme 3

Reagents and conditions: (a) phenyl isocyanate, DBU, DMF, 40 °C; (b) N-succinamidyl-N-methyl carbamate, DBU, DMF, 40 °C.