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. Author manuscript; available in PMC: 2016 Jul 8.
Published in final edited form as: Mod Pathol. 2016 Jan 8;29(2):157–165. doi: 10.1038/modpathol.2015.148

Table 1.

Pathological parameters of discontinuously involved prostate biopsies (n=97)

Gleason Score n (%)

6 35 (36%)
3+4 38(38%)
4+3 15(16%)
>7 9 (9%)

Maximum Tumor Involvement %

Median (range) 70% (20%–100%)
<50% Involvement, n (%) 22 (23%)
≥50% Involvement, n (%) 75 (77%)

IHC staining n (%)

ERG/SPINK1 51 (52%)
ERG+/ERG+ 20 (21%)
SPINK1+/SPINK1+ 2 (2%)
Discordant staining between foci 24 (25%)

Pathological parameters for 97 prostate biopsy cores with discontinuous involvement assessed by dual ERG/SPINK1 immunohistochemistry (IHC). Gleason score, maximum % tumor involvement (inclusive of intervening benign tissue) and ERG/SPINK1 status (of the two foci) are provided for each discontinuously involved core.