Skip to main content
. 2016 Jan 29;11(1):e0147910. doi: 10.1371/journal.pone.0147910

Table 2. Semi-quantitative and quantitative CT perfusion (CTP) Alberta Stroke Program Early CT Score (ASPECTS) in 62 acute ischemic stroke patients categorized according to hemorrhagic transformation (HT) and clinical outcome.

HT (n = 27) no HT (n = 35) p value mRS≤2 (n = 42) mRS>2 (n = 20) p value
Semi-quantitative CTP ASPECTS
CBF (median, IQR, mean ± SD, range) 3, 1.5–4.5, 6.1±2.2, 2–9 6, 4.5–8, 3.3±2.4, 0–9 p<0.0001* 6, 3–8, 5.6±2.7, 0–9 4, 2–5, 3.5±2.2, 0–8 p<0.01*
CBV (median, IQR, mean ± SD, range) 7, 6–9, 7.2±1.8, 3–10 9, 9–10, 9.2±1.0, 6–10 p<0.00001^ 9, 9–10, 8.8±1.4, 6–10 8, 6–8, 7.3±1.9, 3–10 p<0.01^
MTT (median, IQR, mean ± SD, range) 3, 2–5, 3.6±2.5, 0–9 6, 4–8, 6.0±2.4, 2–9 p<0.001* 6, 3–8, 5.6±2.7, 0–9 4, 2–5, 3.8±2.3, 0–8 p<0.02*
CTP mismatch (median, IQR, mean ± SD, range) 4, 2–5, 3.6±2.0, 0–7 3, 1–5, 3.2±2.3, 0–8 p = 0.488* 1, 1–1, 1.0±0.5, 0–2 4, 2–5, 3.5±2.0, 0–6 p = 0.686*
Quantitative CTP ASPECTS
CBF (median, IQR, mean ± SD, range) 4, 2–6, 3.9±2.6, 0–9 7, 5–8, 6.5±2.2, 2–10 p<0.0001* 7, 4–8, 6.1±2.5, 1–10 4, 2–5, 3.8±2.4, 0–8 p<0.001*
CBV (median, IQR, mean ± SD, range) 9, 7–9.5, 8.1±1.9, 4–10 10, 10–10, 9.6±0.9,6–10 p<0.001^ 10, 9–10, 9.3±1.1, 6–10 9, 7–10, 8.1±2.1,4–10 p = 0.021^
MTT (median, IQR, mean ± SD, range) 1, 0–3, 2.0±2.5, 0–9 6, 3–7, 5.1±2.5, 0–9 p<0.0001* 5, 2–7, 4.7±3.0, 0–9 2, 0–2, 1.7±1.7, 0–6 p<0.001*
CTP mismatch (median, IQR, mean ± SD, range) 6, 4–8, 6.1±2.6, 0–10 4, 2,5–7, 4.5±2.6,0–10 p = 0.021* 1, 1–1, 1.0±0.5, 0–2 7, 5–8, 6.4±1.9, 4–10 p<0.02*

CBF = cerebral blood flow; CBV = cerebral blood volume; MTT = mean transit time; SD = Standard deviation; IQR = Interquartile range; mRS ≤ 2 = good outcome; mRS > 2 = poor outcome

statistical analysis = *t-test

^Mann-Whitney.