Table 1.
Univariate general linear model test results showing the effect of time and dose of acute diazinon exposure (i.p.) on adult rat acetylcholinesterase activity in different tissues. If there was an effect of dose Bonferonni post hoc comparisons were made. P < 0.05 in bold.
| Time |
Time*Dose |
Dose |
Bonferonni comparisons with 0 mg/kg, P |
||||||
|---|---|---|---|---|---|---|---|---|---|
| F (df) | P | F (df) | P | F (df) | P | ||||
| 1 mg/kg | 13 mg/kg | 39 mg/kg | |||||||
| Blood | 3.1 (2,74) | .050 | 1.4 (6,74) | 0.245 | 29.3 (3,74) | .000 | .021 | .000 | .000 |
| Cerebellum | 1.1 (2,74) | 0.327 | 0.7 (6,74) | 0.661 | 2.2 (3,74) | 0.094 | |||
| Caudate Putamen | 1.5 (2,74) | 0.231 | 1.6 (6,74) | 0.147 | 8.5 (3,74) | .000 | 1.000 | 1.000 | .000 |
| Hippocampus | 6.5 (2,74) | .002 | 1.1 (6,74) | 0.399 | 8.7 (3,74) | .000 | 1.000 | 0.099 | .000 |
| Prefrontal cortex | 2.9 (2,75) | 0.059 | 1.5 (6,75) | 0.175 | 16.5 (3,75) | .000 | 1.000 | 1.000 | .000 |
| Dorsal raphe nucleus | 1.5 (2,69) | 0.241 | 0.7 (6,69) | 0.667 | 21.3 (3,69) | .000 | 0.412 | .000 | .000 |