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. 2015 Dec 15;157(2):497–507. doi: 10.1210/en.2015-1639

Figure 3.

Figure 3.

PTH-induced urinary cAMP excretion and PTH-induced serum phosphate reduction in GsαSglt2KO are blunted. A, Urine cAMP levels in GsαSglt2KO and control littermates after sc PTH(1–34) injection (50 nmol/kg). Urine was collected at each time point. The results were normalized by the baseline value in each experiment (control; n = 10, 11, 10, 17; GsαSglt2KO; n = 13, 21, 17, 19 at each time point, *, P < .05). B, Serum phosphate level changes in control and GsαSglt2KO littermates 2 hours after sc PTH(1–34) (50 nmol/kg) (n = 11 for control, n = 17 for GsαSglt2KO); P value, below the error bar. C, Renal Cyp27b1 mRNA abundance in control (n = 3, vehicle; n = 6, PTH) and GsαSglt2KO (n = 5, vehicle; n = 5, PTH) littermates 2 hours after sc PTH(1–34) (50 nmol/kg) injection; *, P < .05.