Table 1.
Comparison of Serum Biochemistry and Biomarkers of Bone Formation and Resorption in Male and Female WT and TG Col2.3-WNT16 Mice
| Calcium (mg/dL) | Phosphorus (mg/dL) | ALP (IU/L) | OC (ng/mL) | CTX (ng/mL) | TRAP5b (IU/L) | CTX/TRAP5b | |
|---|---|---|---|---|---|---|---|
| Male | |||||||
| WT | 9.19 ± 0.10 | 10.29 ± 0.44 | 83.5 ± 4.59 | 55.2 ± 5.07 | 34.8 ± 4.80 | 7.00 ± 0.36 | 4.98 ± 0.67 |
| TG | 8.82 ± 0.14 | 9.15 ± 0.54 | 100.8 ± 4.33 | 78.1 ± 6.89 | 30.1 ± 2.85 | 7.03 ± 0.29 | 4.29 ± 0.36 |
| P value | 0.07 | 0.16 | 0.03 | 0.04 | 0.47 | 0.95 | 0.43 |
| Female | |||||||
| WT | 9.18 ± 0.13 | 9.54 ± 0.27 | 116.8 ± 2.55 | 71.8 ± 8.50 | 44.9 ± 7.44 | 8.21 ± 0.32 | 5.53 ± 0.97 |
| TG | 9.17 ± 0.11 | 10.40 ± 0.28 | 121.3 ± 6.40 | 72.0 ± 9.01 | 43.5 ± 9.70 | 10.05 ± 0.51 | 4.29 ± 0.93 |
| P value | 0.98 | 0.08 | 0.59 | 0.98 | 0.91 | 0.02 | 0.37 |
Bold represents significant difference.