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Lack of RL-T1 or RL-D5 decreases circulating RANKL levels. Circulating sRANKL levels of 8-week-old female D6KO, T1KO, and D5KO mice and their littermate controls were measured. The values represent the means ± SD of 3 to 9 mice/group. *, P < .05 vs littermate WT group by t test.
