Table 1.

Serum Chemistry in VMHGsKO and Control Mice on RD or HFD^a

	Female RD		Male RD		Female HFD		Male HFD
	Control	VMHGsKO	Control	VMHGsKO	Control	VMHGsKO	Control	VMHGsKO
Insulin, ng/mL	1.00 ± 0.30	0.82 ± 0.31	1.60 ± 0.38	1.25 ± 0.48	1.38 ± 0.31	0.54 ± 0.03	21.4 ± 6.14	5.82 ± 1.69b
Triglycerides, mg/dL	90 ± 12	81 ± 8	138 ± 17	141 ± 12	122 ± 12	78 ± 8b	112 ± 24	98 ± 12
FFAs, mM	0.63 ± 0.13	0.86 ± 0.08	0.53 ± 0.12	0.82 ± 0.15b	0.74 ± 0.08	0.70 ± 0.09	0.48 ± 0.09	0.45 ± 0.07
Leptin, ng/mL	7.15 ± 2.05	5.21 ± 0.42	7.95 ± 1.25	5.76 ± 1.66	20.5 ± 7.7	10.7 ± 3.8	31.1 ± 5.3	28.5 ± 4.8
Cholesterol, mg/dL	105 ± 7	104 ± 7	138 ± 12	119 ± 9	148 ± 7	129 ± 13	184 ± 6	187 ± 10
Adiponectin, g/mL	13.8 ± 1.4	13.7 ± 0.8	5.4 ± 0.6	5.1 ± 0.3	ND	ND	ND	ND

Abbreviations: FFA, free fatty acid; ND, not done. Data are presented as mean ± SEM.

^aMeasured in 3-month-old mice on a RD or 6.5-month-old mice on 5 months of a HFD (n = 4–7/group).

^bP < .05 vs control littermates.