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. 2015 Dec 14;157(2):679–691. doi: 10.1210/en.2015-1622

Figure 1.

Figure 1.

Male mice were placed on a HFD (45% fat) to promote DIO. After 8 weeks, mice continued on the HFD (control group; n = 8), were placed on an alternate-day calorie deprivation IMF protocol with HFD (IMF-HFD; n = 8), switched to a control LFD (10% fat; n = 8), or placed on placed on IMF protocol with LFD (IMF-LFD; n = 8). Data are represented as means ± SEM. A, Body weights of mice at the end of 4 weeks of the diet intervention. B, Average cumulative food intake (kilocalories) over 4 weeks. *, Difference (P < .05) from HFD; ***, difference from HFD (P < .001).